Squamous cell carcinoma developing in an epidermal inclusion cyst

Squamous cell carcinoma arising in an epidermal inclusion cyst.

An epidermal inclusion cyst is a widespread benign intradermal lesion and may occur anywhere in the body. Normally, it appears as a non-tender, soft mass of variable size. Dissection usually reveals grayish-white or whitish gelatinous materials and a smooth inner surface. The overlying skin almost always shows unremarkable changes. On occasion, the cyst may rupture and induce an inflammatory re...

Squamous Cell Carcinoma Arising from an Epidermal Inclusion Cyst

CONTEXT Cutaneous epidermal cysts are common lesions, but fortunately, malignant transformation of their epithelium is rare. There are few case reports in the literature concerning malignant transformation of an epidermal cyst into squamous cell carcinoma. We present a case of squamous cell carcinoma arising from an epidermal inclusion cyst and describe the clinical and histopathologic findings...

Squamous cell carcinoma originated from an epidermal cyst.

Epidermal cyst (EC) of the skin is a very common condition. Squamous cell carcinoma (SCC) very infrequently arises from EC. A 76-year-old Japanese woman was admitted to our hospital because of multiple papules in the nose and nasal cavity. The clinical diagnosis was sebaceous hyperplasia. An excisional biopsy was obtained from one papule. Histologically, the papule showed an EC. The EC communic...

Squamous Cell Carcinoma Developing in an Intracranial Epidermoid Cyst (cholesteatoma).

Squamous Cell Carcinoma in an Epidermoid Cyst

DESCRIPTION A 63-year-old white man presented with a raised, erythematous tumor on the left side of his nose. The lesion had been present for 3 years, and during the 6 to 8 weeks prior to his presentation, it had become painful. In addition, the cyst had started to drain purulent material when pressure was applied. On physical examination, the tumor was 20 mm in diameter and elevated 5 mm. Ther...